Studies reveal that marijuana and its active constituents, known as cannabinoids, are relatively safe and effective therapeutic and/or recreational compounds. Unlike alcohol and most prescription or over-the-counter medications, cannabinoids are virtually nontoxic to health cells or organs, and they are incapable of causing the user to experience a fatal overdose. Unlike opiates or ethanol, cannabinoids are not classified as central nervous depressants and cannot cause respiratory failure. In fact, a 2008 meta-analysis published in the Journal of the Canadian Medical Association reported that cannabis-based drugs were associated with virtually no elevated incidences of serious adverse side-effects in over 30 years of investigative use.
Studies further reveal that the marijuana plant contains in excess of 60 active compounds that likely possess distinctive therapeutic properties. One recent review identified some 30 separate therapeutic properties—including anti-cancer properties, anti-diabetic properties, neuroprotection, and anti-stroke properties—influenced by cannabinoids other than THC. While not all of these effects have been replicated in clinical trials, many have.